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Issue title: Frontiers in Biomedical Engineering and Biotechnology – Proceedings of the 2nd International Conference on Biomedical Engineering and Biotechnology, 11–13 October 2013, Wuhan, China
Article type: Research Article
Authors: Bernad, Sandor I. | Bosioc, Alin | Bernad, Elena S.; | Craina, Marius L.
Affiliations: Romanian Academy – Timisoara Branch, Centre for Fundamental and Advanced Technical Research, Bd. Mihai Viteazul 24, RO-300223, Timisoara, Romania | University of Medicine and Pharmacy “Victor Babes” Timisoara, Universitary Clinic “Bega”, P-ta Eftimie Murgu 2, RO-300041, Timisoara, Romania
Note: [] Corresponding author. E-mail: elenabernad@mh.mec.upt.ro
Abstract: The long-term success of arterial bypass surgery is often limited by the progression of intimal hyperplasia at the anastomosis between the graft and the native artery. The experimental models were manufactured from glass tubing with constant internal diameter of 8 mm, fashioned into a straight configuration and helical configuration. The aim of this study was to determine the three-dimensional flow structures that occur at the proximal anastomosis under pulsatile flow conditions, to investigate the changes that resulted from variations in the anastomosis angle and flow division, and to establishing the major differences between the straight and helical graft. In the anastomosis domain, a strong region of recirculation is observed near the occluded end of the artery, which forces the flow to move into the perfused host coronary artery. The proximal portion of the host tube shows weak counter-rotating vortices on the symmetry plane. The exact locations and strengths of the vortices in this region are only weakly dependent on Re. A detailed comparison of experimentally measured axial velocity patterns for straight and helical grafts confirm the very strong nature of the secondary flows in the helical geometry. The helical configuration promotes the mixing effect of vortex motion such that the flow particles are mixed into the blood stream disal to the anastomotic junction.
Keywords: Bypass graft, helical graft, hemodynamics, anastomosis
DOI: 10.3233/BME-130877
Journal: Bio-Medical Materials and Engineering, vol. 24, no. 1, pp. 853-860, 2014
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