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Issue title: Frontiers in Biomedical Engineering and Biotechnology – Proceedings of the 2nd International Conference on Biomedical Engineering and Biotechnology, 11–13 October 2013, Wuhan, China
Article type: Research Article
Authors: Chen, Kan | Li, Bin; | Tian, Lian-fang | Zhu, Wen-bo | Bao, Ying-han
Affiliations: School of Automation Science and Engineering, South China University of Technology, Guangzhou, Guangdong, China
Note: [] Address for correspondence: Bin Li, School of Automation Science and Engineering, South China University of Technology, Guangzhou, 510640, Guangdong, China. E-mail: binlee@scut.edu.cn. Telephone and Fax Number: +86-20-87110719.
Abstract: Pulmonary nodules are potential manifestation of lung cancer. Accurate segmentation of juxta-vascular nodules and ground glass opacity (GGO) nodules is an important and active area of research in medical image processing. At present, the classical active contour models (ACM) for segmentation of pulmonary nodules may cause the problem of boundary leakage. In order to solve the problem, a new fuzzy speed function–based active model for segmentation of pulmonary nodules is proposed in this paper. The fuzzy speed function incorporated into the ACM is calculated by the degree of membership based on intensity feature and local shape index. At the boundary of pulmonary nodules, the fuzzy speed function approaches zero and the evolution of the contour curve will stop, so the accurate segmentation of pulmonary nodules can be obtained. Experimental results on juxta-vascular nodules and GGO nodules show that the proposed ACM can achieve accurate segmentation.
Keywords: Image segmentation, boundary leakage, active contour models (ACM), fuzzy speed function, fuzzy clustering
DOI: 10.3233/BME-130840
Journal: Bio-Medical Materials and Engineering, vol. 24, no. 1, pp. 539-547, 2014
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