Searching for just a few words should be enough to get started. If you need to make more complex queries, use the tips below to guide you.
Issue title: Frontiers in Biomedical Engineering and Biotechnology – Proceedings of the 2nd International Conference on Biomedical Engineering and Biotechnology, 11–13 October 2013, Wuhan, China
Article type: Research Article
Authors: Liu, Chengyu; ; | Zheng, Dingchang; | Zhao, Lina | Liu, Changchun
Affiliations: School of Control Science and Engineering, Shandong University, Jinan, 250061, China | School of Information Science and Engineering, Shandong University, Jinan, 250010, China | Medical Physics Department, Newcastle University, Royal Victoria Infirmary, Newcastle Upon Tyne, NE1 4LP, UK
Note: [] Corresponding authors: Tel / Fax: +86-531-88395384, E-mail: bestlcy@sdu.edu.cn and dingchang.zheng@ncl.ac.uk
Note: [] Corresponding authors: Tel / Fax: +86-531-88395384, E-mail: bestlcy@sdu.edu.cn and dingchang.zheng@ncl.ac.uk
Abstract: It has been reported that Gaussian functions could accurately and reliably model both carotid and radial artery pressure waveforms (CAPW and RAPW). However, the physiological relevance of the characteristic features from the modeled Gaussian functions has been little investigated. This study thus aimed to determine characteristic features from the Gaussian functions and to make comparisons of them between normal subjects and heart failure patients. Fifty-six normal subjects and 51 patients with heart failure were studied with the CAPW and RAPW signals recorded simultaneously. The two signals were normalized first and then modeled by three positive Gaussian functions, with their peak amplitude, peak time, and half-width determined. Comparisons of these features were finally made between the two groups. Results indicated that the peak amplitude of the first Gaussian curve was significantly decreased in heart failure patients compared with normal subjects (P<0.001). Significantly increased peak amplitude of the second Gaussian curves (P<0.001) and significantly shortened peak times of the second and third Gaussian curves (both P<0.001) were also presented in heart failure patients. These results were true for both CAPW and RAPW signals, indicating the clinical significance of the Gaussian modeling, which should provide essential tools for further understanding the underlying physiological mechanisms of the artery pressure waveform.
Keywords: Artery pressure waveform analysis, waveform matching, Gaussian function, heart failure
DOI: 10.3233/BME-130808
Journal: Bio-Medical Materials and Engineering, vol. 24, no. 1, pp. 271-277, 2014
IOS Press, Inc.
6751 Tepper Drive
Clifton, VA 20124
USA
Tel: +1 703 830 6300
Fax: +1 703 830 2300
sales@iospress.com
For editorial issues, like the status of your submitted paper or proposals, write to editorial@iospress.nl
IOS Press
Nieuwe Hemweg 6B
1013 BG Amsterdam
The Netherlands
Tel: +31 20 688 3355
Fax: +31 20 687 0091
info@iospress.nl
For editorial issues, permissions, book requests, submissions and proceedings, contact the Amsterdam office info@iospress.nl
Inspirees International (China Office)
Ciyunsi Beili 207(CapitaLand), Bld 1, 7-901
100025, Beijing
China
Free service line: 400 661 8717
Fax: +86 10 8446 7947
china@iospress.cn
For editorial issues, like the status of your submitted paper or proposals, write to editorial@iospress.nl
如果您在出版方面需要帮助或有任何建, 件至: editorial@iospress.nl