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Issue title: Frontiers in Biomedical Engineering and Biotechnology – Proceedings of the 2nd International Conference on Biomedical Engineering and Biotechnology, 11–13 October 2013, Wuhan, China
Article type: Research Article
Authors: Du, Dongxing | Jiang, Song | Wang, Ze | Hu, Yingying | He, Zhaoming; ;
Affiliations: College of Electromechanical Engineering, Qingdao University of Science and Technology, Qingdao, China | College of Mechanics and Materials, Hohai University, Nanjing, China | Department of Mechanical Engineering, Texas Tech University, Lubbock TX, USA | Research Center of Fluid Machinery Engineering and Technology, Jiangsu University, Zhenjiang, China
Note: [] Corresponding author. E-mail: zhaoming.he@ttu.edu.
Abstract: Mitral valve (MV) edge-to-edge repair (ETER) is a surgical procedure for the correction of mitral valve regurgitation by suturing the free edge of the leaflets. The leaflets are often sutured at three different positions: central, lateral and commissural portions. To study the effects of position of suture on left ventricular (LV) fluid mechanics under mitral valve ETER, a parametric model of MV-LV system during diastole was developed. The distribution and development of vortex and atrio-ventricular pressure under different suture position were investigated. Results show that the MV sutured at central and lateral in ETER creates two vortex rings around two jets, compared with single vortex ring around one jet of the MV sutured at commissure. Smaller total orifices lead to a higher pressure difference across the atrio-ventricular leaflets in diastole. The central suture generates smaller wall shear stresses than the lateral suture, while the commissural suture generated the minimum wall shear stresses in ETER.
Keywords: Left ventricular, mitral valve, edge to edge repair (ETER), vortex, atrio-ventricular pressure, wall shear stress
DOI: 10.3233/BME-130795
Journal: Bio-Medical Materials and Engineering, vol. 24, no. 1, pp. 155-161, 2014
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