Affiliations: School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia, Engineering Campus, Penang, Malaysia | Graduate School of Biomedical Engineering, Tohoku University, Sendai, Japan | School of Dental Sciences, Universiti Sains Malaysia, Healthy Campus, Kelantan, Malaysia
Note: [] Address for correspondence: Mariatti Jaafar, School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia, Engineering Campus, 14300 Nibong Tebal, Penang, Malaysia. Tel.: +60 4 5995252; Fax: +60 4 5941011; E-mail: mariatti@eng.usm.my.
Abstract: In present study, a new composition of glass-ceramic was synthesized based on the Na2O–CaO–SiO2–P2O5 glass system. Heat treatment of glass powder was carried out in 2 stages: 600°C as the nucleation temperature and different temperature on crystallization at 850, 950 and 1000°C. The glass-ceramic heat-treated at 950°C was selected as bioactive filler in commercial PMMA bone cement; (PALACOS® LV) due to its ability to form 2 high crystallization phases in comparison with 850 and 1000°C. The results of this newly glass-ceramic filled PMMA bone cement at 0–16 wt% of filler loading were compared with those of hydroxyapatite (HA). The effect of different filler loading on the setting properties was evaluated. The peak temperature during the polymerization of bone cement decreased when the liquid to powder (L/P) ratio was reduced. The setting time, however, did not show any trend when filler loading was increased. In contrast, dough time was observed to decrease with increased filler loading. Apatite morphology was observed on the surface of the glass-ceramic and selected cement after bioactivity test.
Keywords: Bioactive bone cement, polymethylmethacrylate, bioactivity, hydroxyapatite, glass-ceramics
