Affiliations: School of Materials Science and Engineering, Southeast University, Nanjing, P. R. China | School of Public Health, Southeast University, Nanjing, P. R. China | Department of Physics and Materials Science, City University of Hong Kong, Hong Kong, P. R. China | Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, P. R. China
Note: [] Address for correspondence: Prof. Dr. Chenglin Chu, School of Materials Science and Engineering, Southeast University, Nanjing, 211189, P. R. China. Tel.: +86 25 5209 0683; E-mail: clchu@seu.edu.cn.
Abstract: Microstructural characteristics and biocompatibility of a Type-B carbonated hydroxyapatite (HA) coating prepared on NiTi SMA by biomimetic deposition were characterized using XRD, SEM, XPS, FTIR and in vitro studies including hemolysis test, MTT cytotoxicity test and fibroblasts cytocompatibility test. It is found CO32− groups were present as substitution of PO43− anions in HA crystal lattice due to Type-B carbonate. The growth of Type-B carbonated HA coating in SBF containing HCO3− ions is stable during all periods of biomimetic deposition. The carbonated HA coating has better blood compatibility than the chemically-polished NiTi SMA. There was a good cell adhesion to this HA coating surface and cell proliferation in the vicinity of the coating was better than that for the chemically-polished NiTi SMA. Thus biomimetic deposition of this carbonated HA coating is a promising way to improve the biocompatibility of NiTi SMA for implant applications.
Keywords: Carbonated hydroxyapatite, NiTi shape memory alloy, biomimetic deposition
