Affiliations: Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, VA, USA | Department of Mechanical Engineering, Purdue School of Engineering and Technology, IUPUI, Indianapolis, IN 46202, USA | Department of OB/GYN, IU School of Medicine, Indiana University Medical Center, Indianapolis, IN, USA
Note: [] Address for correspondence: Ramana M. Pidaparti, PhD, Professor of Mechanical Engineering, Virginia Commonwealth University, 601 W Main St., Room 306, P.O. Box 843015, Richmond, VA 23284-3015, USA. Tel.: +1 804-827-3742; Fax: +1 804-827-7030; E-mail: rmpidaparti@vcu.edu.
Note: [] Previously at the Department of Mechanical Engineering, Purdue School of Engineering and Technology, IUPUI, Indianapolis, IN 46202, USA.
Abstract: The objective of the present study is to investigate the peak forces for a tracheal smooth muscle tissue subjected to an applied longitudinal vibration following isotonic shortening. A non-linear finite element analysis was carried out to simulate the vibratory response under experimental conditions that corresponds to forced length oscillations at 33 Hz for 1 second. The stiffness change and hysteresis estimated from the experimental data was used in the analysis. The finite element results of peak forces are compared to the experimental data obtained. The comparison of results indicate that the approach and the vibratory response obtained may be useful for describing the cross-bridge de-attachements within the cells as well as connective tissue connections characteristic of tracheal smooth muscle tissue.
