The report of the cartilage regeneration using Total Joint Regeneration System (Internal‐fixator type)

Article type: Research Article

Authors: Aoki, Hideyuki | Tomita, Nohide^; | Harada, Yasuji | Hattori, Koji | Sonobe, Masato | Suguro, Toru

Affiliations: Department of Orthopaedic Surgery, School of Medicine, Toho University, 6‐11‐1 Omorinishi, Ota‐ku, Tokyo 143‐8541, Japan | International Innovation Center (KU‐IIC), Kyoto University, Yoshida‐Hon‐machi, Sakyo‐ku, Kyoto 606‐8501, Japan | Department of Orthopaedic Surgery, Nara Medical University, 840 Shijyou‐cho, Kashihara‐city, Nara 634‐8522, Japan

Note: [] Corresponding author: Naohide Tomita, International Innovation Center (KU‐IIC), Kyoto University, Yoshida‐Hon‐machi, Sakyo‐ku, Kyoto 606‐8501, Japan. Tel. and Fax: +81 75 753 9200, Fax (office): +81 75 771 7286; E‐mail: ntomita@mech.kyoto‐u.ac.jp.

Abstract: A new therapeutic system called the “total joint regeneration system” is proposed as a treatment for osteoarthritis and rheumatoid arthritis. We have developed devices which allow the regeneration of damaged cartilage under noninvasive mechanical stimulation. This paper introduces the basic concepts of total joint regeneration and reports the results of the first animal experiment using an internal‐fixator device using rabbits and a dog.

Keywords: Total joint regeneration, internal‐fixator device, cartilage

Journal: Bio-Medical Materials and Engineering, vol. 13, no. 4, pp. 411-417, 2003