Affiliations: Department of Nuclear Medicine, Cancer Hospital, Peking Union Medical College, Beijing, 100021, China | Department of Nuclear Medicine, General Hospital of PLA, Beijing, 100853, China
Note: [] Corresponding author: Yingmao Chen, Department of Nuclear Medicine, General Hospital of PLA, 28 Fuxing Road, Beijing, 100853, China. E‐mail: chen.ym@263.net.
Abstract: Noise components on PET images were studied. The results showed that the square of synthetic noise Δ2 and the square of signal‐to‐noise ratio (N/Δ)2 varied with the signal intensity N and the relationships were respectively expressed with: Δ2=0.0395N2+0.1427N+0.0025 (R2=0.9358) and (N/Δ)2=−1.13932N2+7.0185N−0.0746 (R2=0.9377). The synthetic noise on PET image may be categorized into three components. The first one varies directly as signal intensity, which depend on random coincidence; the second one varies directly as the square root of signal intensity, which depend on Poisson fluctuation; and the third one is independent of signal intensity.
