A novel magnetic resonance‐positive emission image registration based on morphology

Article type: Research Article

Authors: Ren, Hai‐Ping | Yang, Hu | Ma, Bing‐Rong | Chen, Sheng‐Zu | Wu, Wen‐Kai^;

Affiliations: Department of Nuclear Medicine, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China | Department of Biomedical Engineering, Capital University of Medical Sciences, Beijing, China

Note: [] Corresponding author. Tel.: +86 10 67781331 ext. 8599; Fax: +86 10 67723793; E‐mail: wkwu@public.bta.net.cn.

Abstract: Structures were obtained from images with morphological characteristics to register with voxel‐based method. We applied simple morphological operations to obtain human brain cortex and chose normalized mutual information as similarity measure for the geometric alignment of PET and MR images. Evaluation used nine patients, and the results showed that sub‐voxel accuracy was achieved and the registration process was significantly more rapid. Thus this new automated multi‐modality registration method is more robust and has high accuracy.

Keywords: Morphological tools, MR, PET, 3D registration, mutual information

Journal: Bio-Medical Materials and Engineering, vol. 13, no. 3, pp. 187-196, 2003