Searching for just a few words should be enough to get started. If you need to make more complex queries, use the tips below to guide you.
Article type: Research Article
Authors: Wang, Binyua | Zang, Lianrub; c | Lu, Yingxid | Zhan, Mengyingd | Sun, Tingtingd | Zhou, Yud; | Song, Chenglid
Affiliations: [a] School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China | [b] Center for Biomedical Engineering, School of Information Science and Technology, Fudan University, Shanghai, China | [c] National Heart and Lung Institute, Imperial College London, London, United Kingdom of Great Britain and Northern Ireland | [d] School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China
Correspondence: [*] Corresponding author: Yu Zhou, PhD, Shanghai Institute for Minimally Invasive Therapy, University of Shanghai for Science and Technology, 516 Jungong Road, 200082, Shanghai, China. E-mail: zhouyu_working@163.com
Abstract: BACKGROUND:The clinical outcomes of bipolar radiofrequency (RF) lipolysis, a prevalent non-invasive fat reduction procedure, hinge on the delicate balance between effective lipolysis and patient safety, with skin overheating and subsequent tissue damage as primary concerns. OBJECTIVE:This study aimed to investigate a novel bipolar radiofrequency lipolysis technique, safeguarding the skin through an innovative PID temperature control algorithm. METHODS:Utilizing COMSOL Multiphysics simulation software, a two-dimensional fat and skin tissue model was established, simulating various PID temperature control schemes. The crux of the simulation involved a comparative analysis of different PID temperatures at 45 °C, 50 °C, and 55 °C and constant power strategies, assessing their implications on skin temperature. Concurrently, a custom bipolar radiofrequency lipolysis device was developed, with ex vivo experiments conducted using porcine tissue for empirical validation. RESULTS:The findings indicated that with PID settings of Kp = 7, Ki = 2, and Kd = 0, and skin temperature control at 45 °C or 50 °C, the innovative PID-based epidermal temperature control strategy successfully maintained the epidermal temperature within a safe range. This maintenance was achieved without compromising the effectiveness of RF lipolysis, significantly reducing the risk of thermal damage to the skin layers. CONCLUSION:Our research confirms the substantial practical utility of this advanced PID-based bipolar RF lipolysis technique in clinical aesthetic procedures, enhancing patient safety during adipose tissue ablation therapies.
Keywords: Bipolar radiofrequency lipolysis, PID temperature control algorithm, simulation calculations, skin overheating, thermal damage
DOI: 10.3233/BME-230185
Journal: Bio-Medical Materials and Engineering, vol. 35, no. 3, pp. 303-321, 2024
IOS Press, Inc.
6751 Tepper Drive
Clifton, VA 20124
USA
Tel: +1 703 830 6300
Fax: +1 703 830 2300
sales@iospress.com
For editorial issues, like the status of your submitted paper or proposals, write to editorial@iospress.nl
IOS Press
Nieuwe Hemweg 6B
1013 BG Amsterdam
The Netherlands
Tel: +31 20 688 3355
Fax: +31 20 687 0091
info@iospress.nl
For editorial issues, permissions, book requests, submissions and proceedings, contact the Amsterdam office info@iospress.nl
Inspirees International (China Office)
Ciyunsi Beili 207(CapitaLand), Bld 1, 7-901
100025, Beijing
China
Free service line: 400 661 8717
Fax: +86 10 8446 7947
china@iospress.cn
For editorial issues, like the status of your submitted paper or proposals, write to editorial@iospress.nl
如果您在出版方面需要帮助或有任何建, 件至: editorial@iospress.nl