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Article type: Research Article
Authors: Karayeğen, Gökaya | Koçum, İ. Cengizb; | Çökeli̇ler Serdaroğlu, Dilekb | Doğan, Mustafac
Affiliations: [a] Department of Biomedical Equipment Technology, Başkent University, Bağlıca Campus, 06790 Ankara, Turkey | [b] Department of Biomedical Engineering, Başkent University, Bağlıca Campus, 06530 Ankara, Turkey | [c] Deparment of Control and Automation Engineering, Istanbul Technical University, 34467 Istanbul, Turkey
Correspondence: [*] Corresponding author: İ. Cengiz Koçum, Department of Biomedical Engineering, Başkent University, Bağlıca Campus, 06530 Ankara, Turkey. Tel.: +90 (555) 213 0292; Fax: +90 (312) 246 6660; E-mail: kocum@baskent.edu.tr
Abstract: BACKGROUND:Electrospinning is a highly effective method in order to generate nano-scaled fibers. In conventional electrospinning technique, geometry of nanofibers are mostly random due to the chaotic behavior of polymer jet. OBJECTIVE:Purpose of this study is to produce aligned nanofibers from PVP polymers with advanced electrospinning technique in order to be used in a potential novel sensor applications, tissue regeneration and engineering. METHODS:In this study, by using finite hollow cylinder focusing electrodes, an external electrostatic field is created. With these electrodes, it is aimed to decrease whipping instability of polymer jet. In addition, it is also investigated that the alignment ratio of nanofibers by using conductive parallel electrodes which placed through jet trajectory. RESULTS:In conclusion, with the effect of electrical field created by cylinder electrodes, radius of the fiber dispersion on the collector was able to be reduced and aligned nanofibers were successfully produced by using electrical field generated from the parallel plates. CONCLUSIONS:Radius of the fiber dispersion on the collector is 9.95 mm and fiber diameters varied between 800 nm and 3 μm. Additionally, alignment ratio of the fibers is determined with ImageJ software. These alignment of nanofibers can be used in tissue engineering applications and sensor applications.
Keywords: Aligned nanofibers, whipping instability, alignment ratio, sensor applications
DOI: 10.3233/BME-181017
Journal: Bio-Medical Materials and Engineering, vol. 29, no. 5, pp. 685-697, 2018
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