Dissolution behavior of hydroxyapatite coating by hydrothermal method: An in vitro study

Article type: Research Article

Authors: Zhang, Hongquan | Li, Shipu | Yan, Yuhua | Wang, Youfa

Affiliations: Biomaterials and Engineering Center, Wuhan University of Technology, Wuhan, 430070, P.R.China Fax: +86 27 88780734

Note: [] Corresponding author, present address: Design Institute, Technological University of Mixteca, Huajuapan de Leon, Oaxaca, Mexico C.P. 69000. Fax: +52 953 20214; E‐mail: zhhquan@yahoo.com.

Abstract: Hydroxyapatite (HA) coated CaO–SiO2–B2O3–Na2O glass composites prepared by a hydrothermal coating method were soaked in four kinds of solutions to evaluate the dissolution behavior and the chemical stability. 0.5 mol/l HCl and 0.5 mol/l HNO3 were used as acidic solution, and 5% physiological saline and sodium lactate compound solution as the neutral physiological solution. It was found that HA coated glass composites had the better chemical stability and the corroding‐resistance ability. The dissolution behavior of the HA coating was mainly correlated with the phase composition of the as‐received HA coating and its microstructure as well as the pH value of the solution.

Keywords: Hydroxyapatite coating, hydrothermal method, dissolution behavior, chemical stability, acidic solution, simulated body fluid

Journal: Bio-Medical Materials and Engineering, vol. 10, no. 3-4, pp. 213-219, 2000