Functional brain activity within the medial and lateral portion of BA10 during a prospective memory task

Issue title: Neuropsychology across the Lifespan: Proceedings of the Third Meeting of the Federation of European Societies of Neuropsychology

Article type: Research Article

Authors: Barban, Francesco^; | Carlesimo, Giovanni Augusto^; | Macaluso, Emiliano | Caltagirone, Carlo^; | Costa, Alberto

Affiliations: Clinical and Behavioural Neurology Laboratory, IRCCS Fondazione Santa Lucia, Rome, Italy | Neuroimaging Laboratory, IRCCS Fondazione Santa Lucia, Rome, Italy | Institute of Neurology, University of Rome "Tor Vergata", Rome, Italy

Note: [] Corresponding author: Francesco Barban, Clinical and Behavioural Neurology Laboratory, IRCCS Fondazione Santa Lucia, Rome, Italy. E-mail: f.barban@hsantalucia.it

Abstract: In this study we tested the gateway hypothesis of Broadmann area 10 (BA10). With a functional magnetic resonance imaging (fMRI) protocol we manipulated the saliency – stimulus-oriented (SO) attending – and the memory load – stimulus-independent (SI) attending – during a prospective memory (PM) task. We found a significant main effect of the SO manipulation within the medial BA10 and a significant interaction between SI attending and PM task within the left lateral BA10. Our results give experimental support to the gateway hypothesis.

Keywords: Prospective memory, BA10, Gateway hypothesis

DOI: 10.3233/BEN-2012-129012

Journal: Behavioural Neurology, vol. 26, no. 3, pp. 207-209, 2013