Searching for just a few words should be enough to get started. If you need to make more complex queries, use the tips below to guide you.
Article type: Research Article
Authors: Bolton, D. | Gibb, W. | Lees, A. | Raven, P. | Gray, J.A. | Chen, E. | Shafran, R.
Affiliations: Psychology Department, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK. | Wessex Neurological Centre, Southampton General Hospital, Southampton, UK. | National Hospital for Neurology and Neurosurgery, Queen Square, London, UK. | Department of Psychological Medicine, Royal Free Hospital, London, UK. | Department of Psychiatry, University of Hong Kong, Hong Kong. | Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.
Note: [] Corresponding author: Tel.: +44 171 919 3255; Fax: +44 171 919 3772; E-mail: d.bolton@hkcl.bpmf.ac.uk.
Abstract: While several studies have detected raised levels of neurological soft signs in patients with obsessive compulsive disorder (OCD), the specificity of these abnormalities remains uncertain. This study used a new standardised measure, the Cambridge Neurological Inventory (CNI), to assess soft signs in 51 subjects with OCD. Comparison was made with data on patients with schizophrenia and a non-clinical control group from a previously reported study. Individuals with OCD showed raised levels of soft signs compared with non-clinical controls in many categories of the CNI: Motor Coordination, Sensory Integration, Primitive Reflexes, Extrapyramidal Signs, and Failure of Suppression. Compared with patients with schizophrenia, the OCD group had lower levels of neurological signs in some CNI categories: Hard Signs, Motor Co-ordination, Tardive Dyskinesia, Catatonic Signs, and Extrapyramidal Signs. However, levels of soft signs in the OCD group did not significantly differ from those in the schizophrenia group in other CNI categories: Sensory Integration, Primitive Reflexes and Failure of Suppression. The significance of these patterns of findings is discussed.
Keywords: Obsessive-compulsive disorder, neurological soft signs, schizophrenia, specificity
Journal: Behavioural Neurology, vol. 11, no. 4, pp. 197-204, 1998
IOS Press, Inc.
6751 Tepper Drive
Clifton, VA 20124
USA
Tel: +1 703 830 6300
Fax: +1 703 830 2300
sales@iospress.com
For editorial issues, like the status of your submitted paper or proposals, write to editorial@iospress.nl
IOS Press
Nieuwe Hemweg 6B
1013 BG Amsterdam
The Netherlands
Tel: +31 20 688 3355
Fax: +31 20 687 0091
info@iospress.nl
For editorial issues, permissions, book requests, submissions and proceedings, contact the Amsterdam office info@iospress.nl
Inspirees International (China Office)
Ciyunsi Beili 207(CapitaLand), Bld 1, 7-901
100025, Beijing
China
Free service line: 400 661 8717
Fax: +86 10 8446 7947
china@iospress.cn
For editorial issues, like the status of your submitted paper or proposals, write to editorial@iospress.nl
如果您在出版方面需要帮助或有任何建, 件至: editorial@iospress.nl