An Update of Neural Regulators of the Hypothalamic-Pituitary-Adrenal Axis

Article type: Research Article

Authors: Berczi, Istvan^;

Affiliations: Depatment of Immunology, Faculty of Medicine the University of Manitoba, Winnipeg, MB, Canada | Departmento de Fisiología, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, México

Note: [] Correspondence to: Istvan Berczi, Tel.: +204 789 3509; Fax: +204 789 3921; E-mail: berczii@ms.umanitoba.ca

Abstract: The Hypothalamic coticotropin releasing hormone (CRH) is the major coordinator of acute inflammatory disease (APR). Vasopressin (VP) has a secondary role in acute illness, but when the disease becomes chronic, VP becomes the hypothalamic mediator regulating healing and recovery. During homeostasis VP controls ADIM and INIM, and maintain homeostasis.

DOI: 10.3233/NIB-140099

Journal: Advances in Neuroimmune Biology, vol. 5, no. 4, pp. 217-228, 2014