Prospects on the Origin of Alzheimer's disease

Article type: Meeting Report

Authors: Avila, Jesús^{a; *} | Perry, George^b | Martínez-Martín, Pablo^c

Affiliations: [a] Center of Molecular Biology Severo Ochoa (CSIC-UAM), Madrid, Spain | [b] UTSA Neurosciences Institute and Department of Biology, College of Sciences, University of Texas at San Antonio, San Antonio, TX, USA | [c] UResearch Unit, CIEN Foundation, Carlos III Institute of Health. Alzheimer Center Reina Sofia Foundation. Madrid, Spain

Correspondence: [*] Correspondence to: Jesús Avila, Center of Molecular Biology Severo Ochoa, CSIC-UAM, Campus Cantoblanco, C/ Nicolús Cabrera, 1, 28049, Madrid, Spain. Tel.: +34 91 196 45 64; Fax: +34 91 196 44 20; E-mail: javila@cbm.uam.es.

Abstract: A brainstorming session focused on research into the etiology and pathophysiology of Alzheimer's disease (AD) was held at the Alzheimer Center, Reina Sofia Foundation, Madrid, Spain, on 22 September 2009. The meeting was attended by an international panel of 21 experts and researchers. The meeting started with a call for international research collaboration on AD and neurodegenerative disorders, a need currently encouraged even by political initiatives. The session took place in three stages: 1) a round of individual contributions from participants addressing areas that they considered of interest; 2) a general recommendation whereby studies about prevention and early diagnosis and treatment were to be initiated targeting persons bearing the dominant mutations in AβPP, PS-1 and PS-2 genes that result in development of AD; and 3) a proposal was made to the effect that a network be set up to facilitate interaction among those participating in the meeting.

DOI: 10.3233/JAD-2010-1421

Journal: Journal of Alzheimer's Disease, vol. 20, no. 2, pp. 669-672, 2010